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Description for Protein CHP

calcium binding protein P22
9 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 4/0)
(membrane: 2; platelet: 2)
Summary:
This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • EF: EF-hand, calcium binding motif
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06268
    KEGG - Pathway(s):
    hsa04010; hsa04020; hsa04114; hsa04210; hsa04310; hsa04360; hsa04370; hsa04650; hsa04660; hsa04662; hsa04720; hsa05010; hsa05014
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    SLC9A1BP; Calcineurin B homolog; SLC9A1 binding protein; Calcineurin B homologous protein; Calcium binding protein CHP
    Approved Symbol:

    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06101 Entrez Gene ID: 11261 OMIM ID: 606988 Swissprot Accession: Q99653;