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Description for Protein NUDT4

nudix (nucleoside diphosphate linked moiety X)-type motif 4
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.6.1.52
KEGG - Orthology:
K07766
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
DIPP2; HDCMB47P; KIAA0487; DIPP2beta; DIPP2alpha; Diphosphoinositol polyphosphate phosphohydrolase type 2; Nudix-type motif 4; Nudix-type motif 4 isoform alpha; Nudix-type motif 4 isoform beta; DKFZp686I1281
Approved Symbol:
NUDT4
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 14850 Entrez Gene ID: 11163 OMIM ID: 609229 Swissprot Accession: Q9NZJ9;