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Description for Protein CIT

citron (rho-interacting, serine/threonine kinase 21)
9 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • C1: Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
  • PH: Pleckstrin homology domain.
  • CNH: Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K08282
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    CRIK; STK21; KIAA0949; Citron rho-interacting kinase; Serine/threonine protein kinase 21; Rho-interacting serine/threonine kinase
    Approved Symbol:
    CIT
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 19
    Human (de-) phosphorylation sites: 19; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09289 Entrez Gene ID: 11113 OMIM ID: 605629 Swissprot Accession: O14578;