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Description for Protein ADCY5

adenylate cyclase 5
8 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
ADCY5 belongs to the adenylate cyclase (EC 4.6.1.1) family of enzymes responsible for the synthesis of cAMP (Ludwig and Seuwen, 2002 [PubMed 12503609]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • GuCyclase: Adenylyl-/guanylyl cyclase, catalytic domain
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    4.6.1.1
    KEGG - Orthology:
    K08045
    KEGG - Pathway(s):
    hsa00230; hsa04062; hsa04114; hsa04270; hsa04540; hsa04912; hsa04914; hsa04916; hsa04970; hsa05414
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Adenylate cyclase, type V; ATP pyrophosphate lyase; AC5
    Approved Symbol:
    ADCY5
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE(db);
  • Forskolin(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
    08973_1(11)
    Additional Identifiers:

    HPRD: 08973 Entrez Gene ID: 111 OMIM ID: 600293 Swissprot Accession: O95622;