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Description for Protein ERP29

endoplasmic reticulum protein 29
3 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/0)
(microparticles: 1; platelet: 6; secretome: 1)
Summary:
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09586
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Chromosome 12 open reading frame 8; Endoplasmic reticulum lumenal protein 28; ERp28; Endoplasmic reticulum protein ERp29; ERp31; C12orf8; PDI-DB; Endoplasmic reticulum protein 29 isoform 1 precursor; Endoplasmic reticulum protein 29 isoform 2 precursor
    Approved Symbol:
    ERP29
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 1
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03794 Entrez Gene ID: 10961 OMIM ID: 602287 Swissprot Accession: C9J183; P30040;