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Description for Protein RALBP1

ralA binding protein 1
22 total interacting proteins; 15 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(phosphoproteome: 1; undefined: 1)
Summary:
RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • RHOGAP: GTPase-activator protein for Rho-like GTPases
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08773
    KEGG - Pathway(s):
    hsa05200; hsa05212
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    RalBP1; Ral interacting protein 1; Ral interacting protein, 76 kDa; Dinitrophenyl S glutathione ATPase; DNP SG ATPase; RLIP1; RLIP76; RIP
    Approved Symbol:
    RALBP1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 24
    Human (de-) phosphorylation sites: 24; Platelet phosphorylation sites: 2
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09013 Entrez Gene ID: 10928 OMIM ID: 605801 Swissprot Accession: Q15311;