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Description for Protein GADD45G

growth arrest and DNA-damage-inducible, gamma
32 total interacting proteins; 16 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K04402
KEGG - Pathway(s):
hsa04010; hsa04110; hsa04115
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
GRP17; CR6; DDIT2; Gadd related protein, 17 kD; Growth arrest and DNA damage inducible, gamma; Growth arrest and DNA damage inducible protein GADD45 gamma; Cytokine responsive protein 6; Cytokine responsive gene 6
Approved Symbol:
GADD45G
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05383 Entrez Gene ID: 10912 OMIM ID: 604949 Swissprot Accession: O95257; Q5VZ87;