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Description for Protein SUGT1

SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
5 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 1; undefined: 1)
Summary:
This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TPR: Tetratricopeptide repeats
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12795
    KEGG - Pathway(s):
    hsa04621
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Putative 40-6-3 protein; SGT1, suppressor of G2 allele of SKP1; SGT1B protein; OTTHUMP00000040878; Suppressor of G2 allele of SKP1; SGT1
    Approved Symbol:
    SUGT1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 23
    Human (de-) phosphorylation sites: 23; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09160 Entrez Gene ID: 10910 OMIM ID: 604098 Swissprot Accession: Q9Y2Z0;