Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein BRD8

bromodomain containing 8
13 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • BROMO: bromo domain
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K11321
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Skeletal muscle abundant protein; SMAP; p120; Thyroid hormone receptor coactivating protein; Thyroid hormone receptor interacting protein p120; TrCP120; SMAP2; Skeletal muscle abundant protein 2; Thyroid hormone receptor coactivating protein 120kDa; Bromodomain containing 8 isoform 2; Bromodomain containing 8 isoform 1; Bromodomain containing 8 isoform 3
    Approved Symbol:
    BRD8
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 39
    Human (de-) phosphorylation sites: 39; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04166 Entrez Gene ID: 10902 OMIM ID: 602848 Swissprot Accession: Q9H0E9;