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Description for Protein ADCY3

adenylate cyclase 3
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(membrane: 1; undefined: 1)
Summary:
This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • GuCyclase: Adenylyl-/guanylyl cyclase, catalytic domain
  • CC: Coiled Coil

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    4.6.1.1
    KEGG - Orthology:
    K08043
    KEGG - Pathway(s):
    hsa00230; hsa04020; hsa04062; hsa04114; hsa04270; hsa04540; hsa04740; hsa04912; hsa04914; hsa04916; hsa04962; hsa04970; hsa05110; hsa05414
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    ATP pyrophosphate lyase; AC3; AC-III; KIAA0511; Adenylate cyclase, olfactive type; Adenylyl cyclase, type III
    Approved Symbol:
    ADCY3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
    02620_1(12)
    Additional Identifiers:

    HPRD: 02620 Entrez Gene ID: 109 OMIM ID: 600291 Swissprot Accession: B3KT86O60266