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Description for Protein WASF3

WAS protein family, member 3
4 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 3; undefined: 1)
Summary:
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • WH2: Wiskott Aldrich syndrome homology region 2
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06083
    KEGG - Pathway(s):
    hsa04520; hsa04666
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    WASP family member 3; WASP family protein member 3; WAS protein family, member 3; WASP family Verprolin homologous protein 3; WASP family verprolin homology domain containing protein 3; WAVE3; SCAR homolog of 3; SCAR3; Verprolin homology domain containing protein 3; KIAA0900; RP11-496O3.2
    Approved Symbol:
    WASF3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05458 Entrez Gene ID: 10810 OMIM ID: 605068 Swissprot Accession: Q5T8P4; Q9UPY6; Q86VQ2;