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Description for Protein CGA

glycoprotein hormones, alpha polypeptide
9 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08522
    KEGG - Pathway(s):
    hsa04080; hsa04912; hsa05320
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Glycoprotein hormones, alpha chain; CG alpha; FSH alpha; FSHA; LH alpha; LHA; TSH alpha; TSHA; GPHa; GPHA1; Follitropin Alpha Chain; Follicle-Stimulating Hormone Alpha Chain; Lutropin Alpha Chain; Luteinizing Hormone Alpha Chain, Lsh-Alpha; Thyrotropin Alpha Chain; Thyroid Stimulating Hormone Alpha Chain
    Approved Symbol:
    CGA
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Alpha-D-Mannose(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00342 Entrez Gene ID: 1081 OMIM ID: 118850 Swissprot Accession: P01215; Q6I9S8;