Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein ADCY2

adenylate cyclase 2 (brain)
3 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • GuCyclase: Adenylyl-/guanylyl cyclase, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    4.6.1.1
    KEGG - Orthology:
    K08042
    KEGG - Pathway(s):
    hsa00230; hsa04020; hsa04062; hsa04114; hsa04270; hsa04540; hsa04912; hsa04914; hsa04916; hsa04970; hsa05414
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Adenylate cyclase, brain type II; ATP pyrophosphate lyase; Adenylate cyclase II; 3`,5` cyclic AMP synthetase; KIAA1060; HBAC2
    Approved Symbol:
    ADCY2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE(db);
  • Forskolin(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
    00052_2(12)
    00052_1(10)
    Additional Identifiers:

    HPRD: 00052 Entrez Gene ID: 108 OMIM ID: 103071 Swissprot Accession: Q08462; Q71UM8;