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Description for Protein ZNF274

zinc finger protein 274
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • KRAB: krueppel associated box
  • ZNFC2: zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12458
    KEGG - Pathway(s):
    hsa04722
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Zinc finger protein SP2114; Zinc finger protein HFB101; Zinc finger protein zfp2; Zf2; Zinc finger protein 274 isoform b; Zinc finger protein 274 isoform c; Zinc finger protein 274 isoform a
    Approved Symbol:
    ZNF274
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05682 Entrez Gene ID: 10782 OMIM ID: 605467 Swissprot Accession: Q96GC6;