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Description for Protein ADCY1

adenylate cyclase 1 (brain)
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a form of adenylate cyclase expressed in brain. A similar protein in mouse is involved in pattern formation of the brain. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • GuCyclase: Adenylyl-/guanylyl cyclase, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    4.6.1.1
    KEGG - Orthology:
    K08041
    KEGG - Pathway(s):
    hsa00230; hsa04020; hsa04062; hsa04114; hsa04270; hsa04540; hsa04720; hsa04912; hsa04914; hsa04916; hsa04970; hsa05142; hsa05414
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Adenylate cyclase, type I; ATP pyrophosphate lyase; 3 prime, 5 prime cyclic AMP synthetase; Ca(2+)/calmodulin activated adenylyl cyclase; AC1; Adenyl cyclase, fetal brain, type I
    Approved Symbol:
    ADCY1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Adenosine monophosphate(db);
  • Adenosine triphosphate(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 9
    • Additional Identifiers:

    HPRD: 00053 Entrez Gene ID: 107 OMIM ID: 103072 Swissprot Accession: Q8NFM5; Q08828; Q59FG4;