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Description for Protein GNB5

guanine nucleotide binding protein (G protein), beta 5
17 total interacting proteins; 8 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • WD40: WD40 repeats
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04539
    KEGG - Pathway(s):
    hsa04062
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Transducin beta chain 5; G protein, beta-5 subunit; G protein, beta subunit 5L; Guanine nucleotide-binding protein, beta subunit 5L; Guanine nucleotide-binding protein, beta-5 subunit isoform b; Guanine nucleotide-binding protein, beta-5 subunit isoform a; GB5
    Approved Symbol:
    GNB5
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09191 Entrez Gene ID: 10681 OMIM ID: 604447 Swissprot Accession: O14775;