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Description for Protein PMVK

phosphomevalonate kinase
8 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(microparticles: 1; platelet: 2)
Summary:
PMVK (EC 2.7.4.2) is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate as the fifth reaction of the cholesterol biosynthetic pathway.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.7.4.2
KEGG - Orthology:
K13273
KEGG - Pathway(s):
hsa00900; hsa01100; hsa04146
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
PMK; PMKase; PMKA; PMKI; HUMPMKI
Approved Symbol:
PMVK
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 07404 Entrez Gene ID: 10654 OMIM ID: 607622 Swissprot Accession: Q6FGV9; Q15126;