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Description for Protein PDPN

podoplanin
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Lung type-I cell membrane-associated glycoprotein isoform b; T1A; T1A2; GP36; OTS8; HT1A1; Aggrus; T1alpha 1; T1alpha 2; Podoplanin; Glycoprotein, 36 KD; Gp38; GP40; PA2.26; hT1alpha-1; hT1alpha-2; OTTHUMP00000044504; Lung type-I cell membrane-associated glycoprotein isoform c; Lung type-I cell membrane-associated glycoprotein isoform d; Lung type-I cell membrane-associated glycoprotein isoform a
    Approved Symbol:
    PDPN
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 4 : 1
  • Isoform 3 : 1
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 16398 Entrez Gene ID: 10630 OMIM ID: 608863 Swissprot Accession: Q86YL7; A8MT07;