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Description for Protein CCT7

chaperonin containing TCP1, subunit 7 (eta)
20 total interacting proteins; 10 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 8/1)
(alpha granules: 1; ATP binding: 1; membrane: 2; microparticles: 1; platelet: 3; secretome: 1)
Summary:
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K09499
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
Chaperonin containing TCP1 subunit 7; CCTH; TCP 1 eta; CCT eta; HIV 1 Nef interacting protein; NIP7 1; MGC110985; T-complex protein 1, eta subunit; Chaperonin containing t-complex polypeptide 1, eta subunit; Chaperonin containing TCP1, subunit 7 isoform b; Chaperonin containing TCP1, subunit 7 isoform a
Approved Symbol:
CCT7
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06896 Entrez Gene ID: 10574 OMIM ID: 605140 Swissprot Accession: B7Z4Z7; Q99832; A8MWI8;