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Description for Protein CAP1

CAP, adenylate cyclase-associated protein 1 (yeast)
7 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 15/2)
(alpha granules: 2; membrane: 2; microparticles: 1; phosphoproteome: 1; platelet: 9; secretome: 3; undefined: 1)
Summary:
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CARP: Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    CAP, adenylate cyclase-associated protein 1; CAP; CAP1-PEN
    Approved Symbol:
    CAP1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 14
    Human (de-) phosphorylation sites: 14; Platelet phosphorylation sites: 1
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09869 Entrez Gene ID: 10487 OMIM ID: - Swissprot Accession: Q01518;