Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein SLC9A6

solute carrier family 9 (sodium/hydrogen exchanger), member 6
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants. (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12041
    KEGG - Pathway(s):
    hsa04260
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Sodium/hydrogen exchanger 6; Na(+)/H(+) exchanger 6; NHE-6; Solute carrier family 9 (sodium/hydrogen exchanger), isoform 6 isoform a
    Approved Symbol:
    SLC9A6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
    02208_2(12)
    02208_1(12)
    Additional Identifiers:

    HPRD: 02208 Entrez Gene ID: 10479 OMIM ID: 300231 Swissprot Accession: Q92581; Q3ZCW7; Q86VS0;