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Description for Protein ATP5H

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 6/0)
(membrane: 2; microparticles: 1; platelet: 4)
Summary:
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.6.3.14
    KEGG - Orthology:
    K02138
    KEGG - Pathway(s):
    hsa00190; hsa01100; hsa05010; hsa05012; hsa05016
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d isoform b; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d isoform a; EC 3.6.1.14; EC 3.6.1.34; ATP synthase H+ transporting mitochondrial F1F0 subunit d; ATP synthase D chain mitochondrial; EC 3.6.3.14; My032 protein; ATPQ; ATP5JD
    Approved Symbol:
    ATP5H
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16519 Entrez Gene ID: 10476 OMIM ID: - Swissprot Accession: O75947; A0PJH2;