Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein PPIH

peptidylprolyl isomerase H (cyclophilin H)
6 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 2)
Summary:
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
5.2.1.8
KEGG - Orthology:
K09567
KEGG - Pathway(s):
hsa03040
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
CYPH; CYP-20; PPIase h; USA-CYP; MGC5016; EC 5.2.1.8; SnuCyp-20; Rotamase H; Cyclophilin H; USA-CyP SnuCyp 20; Peptidyl prolyl cis trans isomerase H; U-snRNP-associated cyclophilin SunCyp 20; Small nuclear ribonucleoprotein particle specific cyclophilin H
Approved Symbol:
PPIH
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • L-Proline(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 12084 Entrez Gene ID: 10465 OMIM ID: 606095 Swissprot Accession: O43447; Q6FH36;