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Description for Protein YAP1

Yes-associated protein 1
31 total interacting proteins; 13 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • WW: Domain with 2 conserved Trp (W) residues
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Yes-associated protein 1, 65kDa; YAP65; Yes-associated protein 2; YAP2; YAP
    Approved Symbol:
    YAP1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 51
    Human (de-) phosphorylation sites: 51; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09424 Entrez Gene ID: 10413 OMIM ID: 606608 Swissprot Accession: P46937; Q7Z574; Q8IUY9;