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Description for Protein ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(membrane: 1; platelet: 12; secretome: 2)
Summary:
Sialyltransferases, such as ST3GAL6, catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.4.99.10
    KEGG - Orthology:
    K03792
    KEGG - Pathway(s):
    hsa00601; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Alpha 2,3 sialyltransferase 6; Alpha2,3 sialyltransferase
    Approved Symbol:
    ST3GAL6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 06195 Entrez Gene ID: 10402 OMIM ID: 607156 Swissprot Accession: Q9Y274;