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Description for Protein MYL9

myosin, light chain 9, regulatory
11 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/1)
(microparticles: 1; platelet: 8)
Summary:
Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • EF: EF-hand, calcium binding motif
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12755
    KEGG - Pathway(s):
    hsa04270; hsa04510; hsa04530; hsa04670; hsa04810
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    LC20; MLC2; MRLC1; MYRL2; MGC3505; Myosin RLC; Myosin, light polypeptide 9, regulatory; Myosin regulatory light polypeptide 9 isoform a; Myosin regulatory light polypeptide 9 isoform b; Myosin regulatory light chain 2, smooth muscle isoform
    Approved Symbol:
    MYL9
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 17619 Entrez Gene ID: 10398 OMIM ID: 609905 Swissprot Accession: P24844; Q9BUF9;