Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein MARCH6

membrane-associated ring finger (C3HC4) 6
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
MARCH6 is an E3 ubiquitin (see MIM 191339) ligase that localizes to endoplasmic reticulum (ER) membranes (Hassink et al., 2005 [PubMed 15673284]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • RINGv: The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    6.3.2.19
    KEGG - Orthology:
    K10661
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    KIAA0597; TEB4; Membrane-associated ring finger (C3HC4) 6; RNF176; membrane-associated RING-CH protein VI; Doa10 homolog; Protein TEB-4; RING finger protein 176; E3 ubiquitin-protein ligase MARCH6; EC 6.3.2.-
    Approved Symbol:
    MARCH6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
    11095_1(14)
    Additional Identifiers:

    HPRD: 11095 Entrez Gene ID: 10299 OMIM ID: 613297 Swissprot Accession: O60337;