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Description for Protein DNAJA2

DnaJ (Hsp40) homolog, subfamily A, member 2
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 1)
Summary:
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • DNAJ: DnaJ molecular chaperone homology domain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09503
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    DNAJ; Cell cycle progression restoration gene 3 protein; DnaJ homolog subfamily A member 2; Cell cycle progression 3 protein; DnaJ subfamily A member 2; HIRIP4; CPR3; Dnj3
    Approved Symbol:
    DNAJA2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 5
    Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 07105 Entrez Gene ID: 10294 OMIM ID: 611322 Swissprot Accession: O60884