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Description for Protein CDK5

cyclin-dependent kinase 5
56 total interacting proteins; 26 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 3)
Summary:
(PubMed Links)
Domains and Motifs:
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.22
    KEGG - Orthology:
    K02090
    KEGG - Pathway(s):
    hsa04360; hsa05010
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Cell division kinase 5; PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit; Serine/threonine protein kinase PSSALRE
    Approved Symbol:
    CDK5
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 10
    Human (de-) phosphorylation sites: 10; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 67
    Human phosphorylation targets: 46; Predicted platelet targets: 22
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE(db);
  • Alsterpaullone(db);
  • Flavopiridol(db);
  • Hymenialdisine(db);
  • Indirubin-3'-Monoxime(db);
  • Olomoucine(db);
  • SU9516(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00449 Entrez Gene ID: 1020 OMIM ID: 123831 Swissprot Accession: A1XKG3; Q00535;