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Description for Protein TRIM28

tripartite motif-containing 28
41 total interacting proteins; 12 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • BBOX: B-Box-type zinc finger
  • BBC: B-Box C-terminal domain
  • PHD: PHD zinc finger
  • RING: Ring finger
  • BROMO: bromo domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08882
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Tripartite motif containing protein 28; TIF1B; KAP1; RNF96; KRAB associated protein 1; Nuclear corepressor KAP 1
    Approved Symbol:
    TRIM28
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 48
    Human (de-) phosphorylation sites: 48; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03445 Entrez Gene ID: 10155 OMIM ID: 601742 Swissprot Accession: Q13263;