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Description for Protein AKAP9

A kinase (PRKA) anchor protein (yotiao) 9
25 total interacting proteins; 13 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    YOTIAO; A-Kinase anchor protein 450KD; AKAP450; Centrosome and golgi localized protein kinase N-associated protein; CGNAP; PRKA9; HYPERION; A kinase anchor protein 9 transcript variant 1; Hyperion protein; Centrosome and golgi localized Pkn associated Protein; AKAP350; A-kinase anchor protein 9 isoform 3; A-kinase anchor protein 9 isoform 1; A-kinase anchor protein 9 isoform 2; A-kinase anchor protein 9 isoform 4
    Approved Symbol:
    AKAP9
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 28
    Human (de-) phosphorylation sites: 28; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04921 Entrez Gene ID: 10142 OMIM ID: 604001 Swissprot Accession: Q5GIA7; Q6PJH3; Q99996;