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Description for Protein COL4A3BP

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
9 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • PH: Pleckstrin homology domain.
  • CC: Coiled Coil
  • START: in StAR and phosphatidylcholine transfer protein
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.9
    KEGG - Orthology:
    K08283
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Alpha 3 type IV collagen binding protein isoform 1; Alpha 3 type IV collagen binding protein isoform 2; Goodpasture anitigen binding protein; GPBP; CERTL; StAR related lipid transfer protein 11; StARD11; START domain containing protein 11; STARD11
    Approved Symbol:
    COL4A3BP
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 13
    Human (de-) phosphorylation sites: 13; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05246 Entrez Gene ID: 10087 OMIM ID: 604677 Swissprot Accession: Q9Y5P4; B3KUB7;