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Description for Protein DNAJB6

DnaJ (Hsp40) homolog, subfamily B, member 6
9 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 15)
Summary:
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • DNAJ: DnaJ molecular chaperone homology domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09512
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    DnaJ homolog subfamily B member 6; Heat shock protein J2; MGC1152; HHDJ1; MSJ-1; HSJ-2; MRJ; DnaJ (Hsp40) homolog, subfamily B, member 6 isoform a; DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b; DKFZp566D0824; MGC117297
    Approved Symbol:
    DNAJB6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 07107 Entrez Gene ID: 10049 OMIM ID: 611332 Swissprot Accession: O75190;